Avatrim with Green Tea for Weight Loss

HOW TO LOSE WEIGHT AND INCREASE YOUR ENERGY NATURALLY

Avatrim ingredients are clinically proven to help you lose weight. Avatrims advanced ephedrine free formula is powered by a revolutionary blend of green tea and other potent thermogenic compounds clinically proven to increase the body's metabolic rate and energy expenditure to help promote reductions in weight and body fat*.  This boost to the metabolism promotes a more active healthier lifestyle while trimming down the weight.

Quantity	Regular Price	Our Price
1 Month	$29.95	$29.95
2 Months (Save $10)	$59.90	$49.95
3 Months (Save $15)	$119.80	$74.95
6 Months (2 Free)	$179.70	$119.95

THE AVATRIM PROGRAM WILL HELP YOU:

• Increase Your Energy and Metabolism
• Control Your Appetite
• Burn Fat Safely and Effectively
• Lower Cholesterol
• Increase Thermogenesis
• Enhance Fat Oxidation

You're about to discover what might be the most powerful fat loss system ever developed. It's the same diet program fitness models and bodybuilders use to reach single digit body fat levels and achieve muscle definition that makes them look like walking anatomy charts. Where other programs try to trick your body into losing weight for a while, Avatrim works by making real permanent, healthful changes. Avatrim is the only natural truly effective way to lose weight quickly, safely and permanently!

FIXING THE PROBLEMS WITH YOUR METABOLISM THAT CAUSE WEIGHT GAIN

There are 3 main parts to the Avatrim program the Formula, the Food Plan, and the Activity Plan. Each of these three parts acts individually to positively influence the user's metabolism, in various ways. Taken together, the overall effect of all three major program parts on metabolism is cumulative and very powerful and the reason why Avatrim is called the only correct way to lose weight.

LOSE FAT PERMANENTLY

It's a fact - 95% of the people who go on conventional diets gain all the weight back and sometimes they end up fatter than when they started. Now you can learn how to be in the successful 5% group that keeps it off forever.

LOSE BODY FAT WITHOUT WRECKING YOUR METABOLISM

If you've ever started a diet, then smashed into the dreaded "plateau," it's probably because you cannibalized your own muscle and slowed down your metabolism. Not only will this system teach you the only way to prevent your metabolism from crashing, you will also learn more than a dozen ways to fire up your "metabolic engine" and accelerate your body's natural rate of calorie-burning.

IS YOUR DIET BURNING FAT OR MAKING YOU FATTER?

If you're making the same deadly diet mistakes as most other people, you might lose some weight temporarily, but you'll actually get fatter in the long run. Your body is just way too smart for these "ordinary" diets to ever work - you can't fool a metabolic and hormonal system that's the result of thousands of years of evolution - You have to work with your metabolism, not against it!

CLINICAL STUDIES

Green TeaIn a study reported on in the American Journal of Clinical Nutrition, it was found that green tea extract resulted in a significant increase in energy expenditure, plus also had a significant effect on fat oxidation. While some of the effects were originally theorized to be due to the caffeine content of green tea, the researchers discovered that the tea actually has properties that go beyond those that would be explained by the caffeine.

Today, scientific research in both Asia and the west is providing hard evidence for the health benefits long associated with drinking green tea. For example, in 1994 the Journal of the National Cancer Institute published the results of an epidemiological study indicating that drinking green tea reduced the risk of esophageal cancer in Chinese men and women by nearly sixty percent. University of Purdue researchers recently concluded that a compound in green tea inhibits the growth of cancer cells. There is also research indicating that drinking green tea lowers total cholesterol levels, as well as improving the ratio of good (HDL) cholesterol to bad (LDL) cholesterol.

In a study reported on in the American Journal of Clinical Nutrition, it was found that green tea extract resulted in a significant increase in energy expenditure (a measure of metabolism), plus also had a significant effect on fat oxidation. While some of the effects were originally theorized to be due to the caffeine content of green tea, the researchers discovered that the tea actually has properties that go beyond those that would be explained by the caffeine.

The same amount of caffeine as was in the green tea, administered alone, failed to change energy expenditure in other studies. This led reseachers to believe that there is some interaction going on with the active ingredients of green tea that promotes increased metabolism and fat oxidation.

Clinical Studies

The researchers indicated that their findings have substantial implications for weight control. A 4% overall increase in 24-hour energy expenditure was attributed to the green tea extract, however, the research found that the extra expenditure took place during the daytime. This led them to conclude that, since thermogenesis (the body's own rate of burning calories) contributes 8-10% of daily energy expenditure in a typical cubject, that this 4% overall increase in energy expenditure due to the green tea actually translated to a 35-43% increase in daytime thermogenesis.

Clinical Study

Of critical importance to thyroid patients is the fact that none of the research subjects reported any side effects, and no significant differences in heart rates were noticed. In this respect, green tea extract is different from some of the prescription drugs for obesity, and herbal products like ephedra, which can raise heart rates and blood pressure, and are not recommended for many individuals, in particular, those with thyroid disease who may be particularly sensitive to stimulants.

SOURCE: Nagao, T. American Journal of Clinical Nutrition, January 2005; vol 81: 122-129.

INGREDIENTS

Green tea and Camellia Sinensis Leaf

Avatrim Green tea is made from the dried leaves of Camellia sinensis, which is an evergreen shrub. Green tea, a minimally processed variety of tea, is first withered then dried immediately after picking to halt oxidation. Recently, much has been said about the antioxidant properties of the constituents of green tea. The active constituents include catechins and polyphenols. Tea extracts formulated for high-polyphenol content contain the greatest amounts of beneficial substances as they are highly concentrated formulations.

Human studies have assessed the effect of green tea extract (GTE) capsules on weight loss and weight maintenance in average weight and overweight individuals. (Shixian Q et al. J Med Food. 2006; Wang X et al. Biochem Biophys Res Commun. 2001; Cooper R, et al. J Altern Complement Med. 2005; Murase T et al. Int J Obes Relat Metab Disord. 2002; Sayama K. In Vivo. 2000). It is being compared to Ephedra, which is a popular product being used for weight loss. The physiological effects of green tea are in fact similar to ephedra for obesity. Green tea increases the 24 hour energy expenditure, fat oxidation and thermogenesis.

Thermogenesis, a process of energy generation at the cellular level, plays an important role in the proper utilization of food and nutrients. The stored body fat can also be utilized by this process. Thus it reduces the total fat content of the body. The study showed that the weight loss associated with intake of GTE is due to an increase in thermogenesis. This is attributed to the catechins, especially epigallocatechin gallate, which also potentiates the thermogenic property of caffeine, present in green tea. (Shixian et al . J Med Food. 2006). Green tea extract inhibits the breakdown of Norepinephrine, which is an important hormone responsible for the breakdown of fat. Regarding green tea and thermogenesis, a study examining the benefits of functional food products for the management of weight showed that green tea increased energy expenditure over a 24-hour period.

Catechins have been shown to decrease the synthesis of fatty acids and also reduce the cholesterol levels in the blood. (Shixian et al . J Med Food. 2006; Cooper R, et al. J Altern Complement Med. 2005; Murase T et al. Int J Obes Relat Metab Disord. 2002). Researchers in Japan found that green tea by suppressing lipid metabolism, also suppresses fat accumulation in the body and thus body weight and body weight increases, and decreased leptin levels, which  are all tied to obesity(Sayama K in In Vivo, 2000). Green tea may also reduce the digestibility of dietary fats via inhibition of enzymes required for fat digestion.

There are no established doses for the benefits of green tea or green tea extract. One cup of tea contains approximately 80-100 mg of polyphenols and 50 mg of caffeine. Regarding safety, the caffeine content of green tea is responsible for most of the side effects like insomnia, increase in the heart rate, increased urination and psychological dependence. Preliminary reports show that consumption of green tea may be associated with estrogen deficiency, but there is no conclusive evidence that it may cause hot flashes.

Biotin

Biotin is a water soluble vitamin that belongs to the vitamin B-complex family. It plays an important role in the metabolism of carbohydrates and fats. It helps in providing energy, promoting health of hair, important for growth and for the health of the central nervous system. Recently, it has been shown to have metabolic effects that promote energy utilization and fight insulin resistance, the two important factors in weight gain and obesity. (Zhang et al. Journal of Nutritional Science and Vitaminology. 1996, Reddi et al .  Life Sciences. 1998. Reddi et al  in Life Sciences, 1998).

In humans, it is proven to improve the glucose tolerance, and its important role in the metabolism of glucose has been commented upon. (Koutsikos et al . Renal Failure, 1996). Insulin resistance leads to hyperinsulinism (increased levels of insulin in the blood). Hyperinsulinism, in turn, leads to increase in fat synthesis in adipocytes and is strongly linked to obesity. In addition, resistance to insulin also compromises on the efficiency of insulin mediated thermogenesis, which leads to an increase in the weight gain.

Biotin improves the efficiency of insulin action and can thus promote weight loss. The recommended daily allowance (RDA) for biotin is 300 micrograms. No side effects of biotin have been reported at doses of even 10 mg per day. Sources rich in this vitamin include liver, kidney, molasses, peas, avocado and green leafy vegetables.

L-Carnitine

L-Carnitine is an amino acid, essential for fatty acid oxidation, mitochondrial function and energy production in the cells. It transports fat into the mitochondria and thus helps in fat metabolism. It increases fatty-acid oxidation and glucose utilization. In a clinical trial involving healthy individuals, oral l-carnitine demonstrated a reduction in the total fat mass, increased the muscle mass and a favorable effect on fatigue and serum lipids, thus it increased weight loss without altering the fat to lean body mass ratio. (Kelly GS. Altern Med Rev. 1998).L-Carnitine is found in meat and dairy products or is synthesized from other amino acids (lysine and methionine) in the liver and kidney. As it is a non-essential amino acid, no RDA values have been established. However, doses upto 2-6 gms/day have been used for various conditions. Consumption of oral supplements may be associated with nausea, abdominal cramps and diarrhea, but no significant side effects have been observed.

Alpha-Lipoic Acid

Alpha-lipoic acid (ALA) also known as thioctic acid is a naturally occurring antioxidant that plays an important role in energy reactions in the body and also helps the body to utilize glucose.

Researchers have shown that ALA reduces body weight and prevents development of diabetes in diabetes prone rats by improving the insulin sensitivity.( Lee et al . Biochem Biophys Res Commun. 2005). ALA mitigates the insulin resistance in them via an anti-oxidative mechanism. (Bitar MS et al in Horm Metab Res. 2004). It has been shown that ALA-induced improvement of insulin sensitivity is by activation of an enzyme called AMPK and reduced triglyceride accumulation in skeletal muscle. It acts on the hypothalamus and suppresses the food intake in addition to increasing the energy expenditure. This mechanism also plays an important role in its anti-obesity effect. (Kim MS in Nature Med 2004). There are no current recommendations regarding the dosage of ALA. Food sources of ALA include spinach, broccoli, beef and kidney.

R-Lipoic acid

R-lipoic acid (RLA) is the naturally occurring form of lipoic acid and is also the biologically active form of lipoic acid. S-lipoic acid (SLA) is a form of lipoic acid that is synthetically created during the production of lipoic acid. SLA is less effective than RLA, and at higher concentrations, it may inhibit mitochondrial metabolism.

RLA is a powerful antioxidant and also lowers blood sugars by being a mimic of insulin. It causes a significant increase in the insulin sensitivity, increases metabolic rate and decreases the fat gain in the body. (Jacob S et al . Free Rad Biol Med. 1999, Moines H et al . Arch Biochem Biophys. 2002). It decreases the level of serum lactate and pyruvate in diabetic patients, improves the glucose uptake by cells. ( Korotchkina et al . Free Radical Res. 2004).

Piper Nigrum and Bioperine

Piper nigrum is commonly known as black pepper, has long been advocated for various complaints as an active ingredient in several Ayurvedic preparations. It also has a role in weight loss. Two of its active ingredients; bioperine and piperine are especially effective. It has recently been investigated and very encouraging results are found. Several mechanisms are postulated to play a role in the loss of weight.

Piperine has been shown to decrease the total lipid content in the rat testes via inhibition of enzymes involved in fat synthesis. (MaliniT et al. Biochem Mol Biol Int. 1999).

Bioperine, enhances thermogenesis and therefore increases the energy expenditure.
A study has shown that alkamides isolated from the fruit of piper nigrum inhibit an enzyme called diacylglycerol acyltransferase. This inhibition of this enzyme has emerged as a therapeutic target in the management of obesity. (Lee SW et al in J Agric Food Chem. 2006)
It is also known to enhance the absorption of nutrients in the intestine, which is important in maintaining a healthy metabolic state.
References

1.     Kelly GS. L-Carnitine: therapeutic applications of a conditionally essential amino acid. Altern Med Rev. 1998 Oct;3(5):345-60.
2.     Lee WJ, Song KH, Koh EH, Won JC, Kim HS, Park HS, Kim MS, Kim SW, Lee KU, Park JY. Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle. Biochem Biophys Res Commun. 2005;332(3):885-887
3.     Shixian Q, VanCrey B, Shi J, Kakuda Y, Jiang Y. Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-O-methyltransferase. J Med Food. 2006;9(4):451-8
4.     Malini T, Arunakaran J, Aruldhas MM, Govindarajulu P. Effects of piperine on the lipid composition and enzymes of the pyruvate-malate cycle in the testis of the rat in vivo. Biochem Mol Biol Int. 1999;47(3):537-45
5.     Lee SW,Rho MC, Park HR ,et al .Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum. J Agric Food Chem. 2006;54(26):9759-63
6.     Bitar MS, Wahid S, Pilcher CW,Al-Saleh E, Al-Mulla F. Alpha-lipoic acid mitigates insulin resistance in Goto-Kakizaki rats. Horm Metab Res. 2004;36(8):542-9..
7.     Reddi A.; DeAngelis B.; Frank O.; Lasker N.; Bakura H. Biotin supplementation improves glucose and insulin tolerances in genetically   diabetic KK mice. LIFE SCI. 1988, 42(13):1323-1330
8.     Zhang H.; Osada K.; Maebashi M.,Ito M., Komai M., Furukawa Yand H. ZhangA high biotin diet improves the impaired glucose tolerance of long-term spontaneously hyperglycemic rats with non-insulin-dependent diabetes mellitus. Journal of Nutritional Science and Vitaminology (Japan).1996;42(6):517-526
9.     O'Meara S, Riemsma R, Shirran L, Mather L, ter Riet G. A rapid and systematic review of the clinical effectiveness and cost-effectiveness of orlistat in the management of obesity. Health Technol Assess. 2001; 5(18):1-81.
10.   Sayama K et al. Effects of green tea on growth, food utilization and lipid metabolism in mice. In Vivo 2000; 14(4):481-4.
11.   Wang X et al. "Green tea epigallocatechin gallate: a natural inhibitor of fatty-acid synthase." Biochem Biophys Res Commun2001;288: 1200-1208
12.   Cooper R, Moore DJ and Morre DM. medicinal beneifits of green tea:Part I. review of non-cancer benefits. J Altern Complement Med. 2005;11(3):521-52822.
13.   Murase T et al. "Beneficial effects of tea catechins on diet-induced obesity: stimulation of lipid catabolism in the liver. Int J Obes Relat Metab Disord. 26, 11:1459-64, 2002.
14.   Koutsikos D.; Fourtounas C.; Kapetanaki A., et al .Oral glucose tolerance test after high-dose i.v. biotin administration in normoglucemic hemodialysis patients. Renal Failure. 1996;18(1):131-137
15.   Kim MS, Park JY, Namkoong C et al. Anti-obesity effects of alpha-lipoic acid mediated by suppressionof hypothalamic AMP-activated protein kinase. Nat Med. 2004;10(7):727-33
16.   Jacob S, Rues P, Hermann R. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Rad Biol Med. 1999;27(3-4):309-14
17.   Moines H, Trios O, Park YC, Chow KJ, Packer L R-alpha-Lipoic Acid Action on Cell Redox Status, the Insulin Receptor, and Glucose Uptake in 3T3-L1 Adipocytes. Arch Biochem Biophys. 2002;15:397(2): 384-91.
18.   Korotchkina LG, Sidhu S and Patel MS. R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase. Free Radical Res. 2004;38:1083-1092
19.   WHO. Available on. http://www.who.int/mediacentre/factsheets/fs311/en/index.html Accessed on 10/02/07
20.   CDC. Available at. http://www.cdc.gov/nccdphp/dnpa/obesity/faq.htm#doing Accessed on 10/02/07
21.   Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults. National Institutes of Health, National Heart, Lung, and Blood Institute. September 1998.
22.   National Health and Nutrition Examination Survey (NHANES). Available at. http://win.niddk.nih.gov/publications/PDFs/stat904z.pdf Accessed on 10/02/2007.

FREQUENTLY ASKED QUESTIONS

What does Avatrim do?
Avatrim is an exclusive formulation of research-supported botanical ingredients designed to support a healthy diet. Our goal was simple... developing a product that increases your metabolism, increases your energy, and controls your appetite.

What are the Ingredients of the Avatrim Formula?
Acetyl L-Carnitine, Green Tea, Camellia Sinensis, Alpha Lipoic Acid, Bioperine, Piper Nigrum, and Biotin.

What is the recommended dose?
As a dietary supplement, adults should take one capsule twice a day with a meal or as directed by your physician.

Are there any side effects?
Avatrim is natural. There are no known interactions with any other herbal dietary supplement or drug. Our Avatrim contains no ephedra, no ma huang, and no ephedrine of any kind and are extremely safe if taken as directed.

Is the packaging discreet?
Yes, all orders are shipped in a discreet package.

ABOUT AVATRIM

Avatrim manufactures Herbal Treatment products along with a wide variety of herbal supplements, liquid formulas and capsule products.

We create unique, safe and effective products that help people supplement their lives. Avatrim has formulated a unique and highly effective line of herbal dietary and other supplements. It is our goal to provide retailers and vendors with the finest quality supplements ever made at wholesale prices barely above our manufacturing costs.

We are proud to offer a wide range of "high demand" herbal supplements made only from the finest pharmaceutical grade ingredients available.
Avatrim Quality Control

All of our raw materials must pass stringent quality controls before they are utilized. In addition, we use only those precursor materials that are of the highest quality and that pass our in house quality inspection.

All raw materials are tested for purity prior to production. Quality control engineers have the authority during any stage of production to reject any product that does not adhere to our strict quality standards. All personnel follow explicit written protocols that are strictly enforced during the manufacturing process. All steps during the manufacturing process are documented and reviewed by quality control specialists.

Manufacturing equipment is properly maintained and cleaned on a predetermined schedule that is documented in company logs for review by the Department of Agriculture. This helps to ensure the absence of any contamination during the manufacturing process. Production records associated with each unit of a product, including all raw materials used, are filed for two years past the expiration date.
Further quality control is demonstrated by:

Product analysis This is recorded for each product that is manufactured. The analysis contains the specific components of the herbal product, including a lot number for each of the ingredients, as well as the production methods used.

Raw materials These are purchased only from reputable wholesalers. Each raw material in our products must come with a Certificate of Analysis obtained from the supplier. Our in house Quality Assurance team also analyzes the raw materials for authenticity.

Packaging material All packaging materials are purchased only from reputable wholesalers. Specific Quality Assurance personal ensure that all labels are assigned to the proper products to avoid any confusion. All new labels are cross checked with the original master label to make certain that there have been no mistakes during the printing process.

Lot Numbers Once an order request has been received, the herbal supplement to be manufactured is entered in the production records and a lot number is assigned. The raw materials are released to the pharmacy after all products have been checked for authenticity.
Avatrim Manufacturing Guidelines

In addition to the protocols described above, Avatrim Supplements adheres to the following manufacturing guidelines to ensure the utmost quality control:

Blending and Granulation All equipment used in the process of mixing and granulation is inspected by the Director of Operations prior to use. Raw materials are then inspected for the final time. The lots are then processed using strict written guidelines for each herbal product. Following granulation and blending, the powder blends are stored in specially designed containers to ensure freshness and to avoid any contamination. Once again the Director of Operations ensures that all new blends are labeled appropriately.

Encapsulation and Compression Once a test unit has been processed, a sample is unit is issued to Quality Assurance to be compared to retained samples in order to ensure product integrity. Once the new unit has been approved by Quality Assurance, full line production may begin. Quality Assurance inspections are conducted using set protocols for the capsules. As with the blending and granulation process, the capsules are stored in specifically designed containers to ensure freshness and to avoid any contamination. The Director of Operations makes certain that all new capsules are labeled appropriately.

Liquids Liquid products are prepared following the same stringent protocols described above for blending, granulation, encapsulation and compression.

Packaging and Inspection Upon completion of processing, the final product is inspected again by the Quality Assurance staff. Broken tablets, over filled capsules and any other defective products are removed from the lot. Products released by the Quality Assurance staff are subsequently either packaged for bulk storage or bottled and labeled for consumer use (labels contain the appropriate information required by the Federal Drug Administration; batch numbers are logged). All finished products are properly labeled and closed with a tamper proof seal. The Quality Assurance unit also retains samples of raw materials for one year past the expiration date of the last product they are used in. The unit also retains samples of finished products for one year past the product expiration date. These samples are maintained under controlled conditions.

Final Products All final products are stored in quarantine in a climate controlled environment until final delivery to the customer.

All Avatrim Supplements are manufactured using Good Manufacturing Practices set forth by the US Federal Drug Administration. In addition, both scheduled and surprise inspections by the Quality Assurance staff during different aspects of the manufacturing process help to ensure specific quality, strength and purity for both the raw materials and the finished supplements.